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Severe nausea leading to discontinuation of treatment occurred in a minority of participants
About 12 percent of Americans have tried a GLP-1, RAND reports
The short answer is no: combining these drugs is medically unsafe and can trigger severe side effects including uncontrolled blood sugar drops, extreme nausea, and heart rhythm problems
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Clinical trials demonstrate that tirzepatide significantly reduces A1C levels through its dual action on GIP and GLP-1 receptors, improving insulin secretion, slowing gastric emptying, and reducing glucagon release
We will further look into this and explore how we can help patients with addiction, potentially with GLP-1, Lange said, also adding that it has to be addressed in a scientific, and obviously also from a regulatory perspective, very rigorous way so we can really see the potential impact of GLP-1 in that space. However, in response to questions from Biospace, a Novo spokesperson said that Lange was referring to the already ongoing work studying semaglutide on liver damage and alcohol use in its phase 2 trial, and that the company has no plans to study the drug in broader addiction indications
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